Home
 
News
 
About p53
 
Structure
 
 
Analysis Tools
 
 
 
 
 
 
Help
 
About Us
 
Acknowledgement
 
Links
 
FAQs
 
Feedback
 
 
 
  Analysis Tools  
     
     
DNA Conservation
 
The user is able to assess the conservation of the p53 genomic DNA sequence across various species through Multiple Sequence Alignment using ClustalW. Users are able to choose the sequences for the Multiple Sequence Alignment and subsequent analysis of the results can be viewed through JalView.
 
Protein Conservation
 
The user is able to assess the conservation of the p53 amino acid sequence across various species through Multiple Sequence Alignment using ClustalW. Users are able to choose the sequences for the Multiple Sequence Alignment and subsequent analysis of the results can be viewed through JalView.
 
Structural Mutation
 
The Structural Mutation Analysis Tool allows the user to perform point mutations on a human p53 wildtype structure and view the results comparatively using JMol. Mutant PDBs were generated using Swiss PDB Viewer 3.7 by choosing the best rotamer conformation of the mutant amino acid.
 
2° Structure Prediction
 
This tool predicts the secondary structure of p53 in various species using the amino acid sequence.
 
Sequence Finder
 
The user is able to find out if a particular sequence, nucleotide or amino-acid, is contained within the p53 gene or protein. It also allows the user to directly access the respective sequence viewers if the sequence is found.
 
 
   
 
Copyright © 2005
Terms of Use
Bioinformatics Institute