| URN | urn:agi-ProtModification:inout-urn:agi-llid:983: |
|---|---|
| Nodes | CDC2; wortmannin; CCNA2; toxin; WEE1; MAPK14; CAT; antioxidant; CDC25C; TP53 |
| Modification Type | dephosphorylation |
| References | 11 |
| Connectivity | 10 |
| MedLine Reference | 15149864:7 |
|---|---|
| Sentence | In addition, we found that wortmannin treatment inhibits dephosphorylation of the tyrosine inhibitory site of CDK1. |
| MedLine Reference | 14767478:3 |
|---|---|
| Sentence | We report here that reducing cyclin A expression by RNA interference (RNAi) in primary human fibroblasts inhibited activation of Cdc25B and Cdc25C and dephosphorylation of Cdk1 on tyrosine (tyr) 15. |
| MedLine Reference | 11240139:0 |
|---|---|
| Sentence | The bacterial cytolethal distending toxin (CDT) triggers a G2/M cell cycle arrest in eukaryotic cells by inhibiting the CDC25C phosphatase-dependent CDK1 dephosphorylation and activation. |
| MedLine Reference | 15175024:5 |
|---|
| MedLine Reference | 15182534:6 |
|---|
| MedLine Reference | 11488607:8 |
|---|
| MedLine Reference | 9278510:1 |
|---|
| MedLine Reference | 14711880:3 |
|---|
| MedLine Reference | 7539047:7 |
|---|
| MedLine Reference | 9486797:3 |
|---|
| MedLine Reference | 9699647:4 |
|---|