Regulation :

Effect positive
URN urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-llid:3725::positive
Nodes TP53 --+> JUN
References 6
Connectivity 2

MedLine Reference 12963547:5
Sentence Radiation-induced Fas sensitization in prostate cancer cell was mediated through p53-dependent transactivation of the Fas gene, which can be blocked by androgen stimulation mainly through induction of c-jun.

MedLine Reference 9661907:4

MedLine Reference 11514621:1271

MedLine Reference 11287606:1373

MedLine Reference 10551785:1132

Sentence Elevated c-Jun was also shown to repress transcription of the tromobospondin 1 gene (Mettouchi et al., 1994 ), which is activated by p53 (Dameron et al., 1994 ).