| URN | urn:agi-Expression:inout-urn:agi-llid:1432:out-urn:agi-llid:3725::positive |
|---|---|
| Nodes | MAPK14 --+> JUN |
| References | 6 |
| Connectivity | 2 |
| Effect | positive |
| MedLine Reference | 11156425:1124 |
|---|---|
| Sentence | Activation of c- jun transcription is mediated by JNK and p38 MAPK, which phosphorylate ATF-2 and c-Jun bound to the AP-1 site in the promoter of c- jun (12) . |
| MedLine Reference | 11888903:1200 |
|---|---|
| Sentence | ERKs and p38 kinase were found to induce expression of c-Jun and c-Fos, leading to increased AP-1 transcriptional activity. |
| MedLine Reference | 11108246:1370 |
|---|
| MedLine Reference | 10727463:1316 |
|---|
| MedLine Reference | 9425017:1270 |
|---|
| MedLine Reference | 10330170:7 |
|---|---|
| Sentence | Moreover, in addition to JNK, ERK5, p38alpha, and p38gamma were found to stimulate the c-jun promoter by acting on distinct responsive elements. |