| Effect | positive |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-go:0005125::positive |
| Nodes | TP53 --+> cytokine activity |
| References | 3 |
| Connectivity | 2 |
| MedLine Reference | 10196169:1193 |
|---|---|
| Sentence | Possibly, the induction of Cox-2 by oncogenes ( 9 , 11 ), growth factors ( 42 ), and cytokines ( 6 ) may be enhanced in cells expressing mutant p53. |
| MedLine Reference | 12517948:1251 |
|---|---|
| Sentence | Collectively, these data suggest that p21 may be one of the nodal points through which p53 inhibits cytokines and MMPs (Fig. 9 ). |
| MedLine Reference | 8643473:12 |
|---|