| Effect | positive |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:1432:out-urn:agi-go:0004199::positive |
| Nodes | MAPK14 --+> caspase |
| References | 12 |
| Connectivity | 2 |
| Journal | J. Exp. Med |
|---|---|
| Journal Reference | v191 i6 p1017 (2000) |
| Journal Link | http://www.jem.org/cgi/content/full/191/6/1017 |
| Journal | J. Exp. Med |
|---|---|
| Journal Reference | v191 i6 p1017 (2000) |
| Journal Link | http://www.jem.org/cgi/content/full/191/6/1017 |
| Journal | J. Exp. Med |
|---|---|
| Journal Reference | v191 i6 p1017 (2000) |
| Journal Link | http://www.jem.org/cgi/content/full/191/6/1017 |
| Journal | J. Exp. Med |
|---|---|
| Journal Reference | v191 i6 p1017 (2000) |
| Journal Link | http://www.jem.org/cgi/content/full/191/6/1017 |
| Journal | J. Exp. Med |
|---|---|
| Journal Reference | v191 i6 p1017 (2000) |
| Journal Link | http://www.jem.org/cgi/content/full/191/6/1017 |
| Journal | J. Exp. Med |
|---|---|
| Journal Reference | v191 i6 p1017 (2000) |
| Journal Link | http://www.jem.org/cgi/content/full/191/6/1017 |
| MedLine Reference | 12473116:1187 |
|---|---|
| Sentence | In this study, we found that Py/Zn- induced apoptosis was mediated by activation of caspases followed by rapid activation of p38MAPK . |
| MedLine Reference | 11555660:1163 |
|---|---|
| Sentence | Inhibition of p38 MAP kinase prevents nitric oxide-induced release of cytochrome c and caspase activation in neural progenitor cells. |
| MedLine Reference | 10908576:1167 |
|---|
| MedLine Reference | 10727463:1014 |
|---|
| MedLine Reference | 11461973:1206 |
|---|
| MedLine Reference | 12805646:9 |
|---|---|
| Sentence | Inhibition of p38 MAP kinase by SB203580 blocked all downstream effects of Bax translocation, including cytochrome c release, caspase activation, and internucleosomal DNA fragmentation. |