| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:1432:out-urn:agi-cellproc:permeation::unknown |
| Nodes | MAPK14 ---> permeation |
| References | 2 |
| Connectivity | 2 |
| Journal | AJRCMB |
|---|---|
| Journal Reference | v28 i5 p574 (2003) |
| Journal Link | http://ajrcmb.atsjournals.org/cgi/content/full/28/5/574 |
| MedLine Reference | 12707013:1163 |
| Sentence | We found that p38 MAPK is a critical mediator of TNF- �induced microtubule disassembly, actin microfilament rearrangement, and endothelial permeability. |
| MedLine Reference | 15388671:4 |
|---|---|
| Sentence | These data indicate that the activation of p38 MAPK by UVB engages a caspase-independent death signal leading to mitochondrial membrane permeabilization and apoptosis in human keratinocytes and suggest that p38 MAPK might have a preventive role in the process of photocarcinogenesis. |