| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:1432:out-urn:agi-cellproc:mortality::unknown |
| Nodes | MAPK14 ---> mortality |
| References | 1 |
| Connectivity | 2 |
| MedLine Reference | 12618232:5 |
|---|---|
| Sentence | Female transgenics, despite similar contractile dysfunction, displayed a temporal delay in p38 activation, hypertrophy, and mortality (22 months), which was associated with sustained cardiac levels of MAP Kinase Phosphatase-1 (MKP-1), a potent inhibitor of p38. |