| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-cellproc:mortality::unknown |
| Nodes | TP53 ---> mortality |
| References | 1 |
| Connectivity | 2 |
| MedLine Reference | 12858174:8 |
|---|---|
| Sentence | Impairment of this pathway may enhance spontaneous mutation frequency and activate p53-dependent apoptotic pathway(s) in vivo, causing severe renal failure, growth retardation and early mortality. |