| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:1432:out-urn:agi-cellproc:focal%20contact::unknown |
| Nodes | MAPK14 ---> focal contact |
| References | 4 |
| Connectivity | 2 |
| MedLine Reference | 11120848:1030 |
|---|---|
| Sentence | Recently it has been observed that the p38 MAP kinase is phosphorylated within minutes of cross-linking L-selectin, and inhibition of p38 MAP kinase has been shown to inhibit L-selectin-dependent neutrophil shape change, adhesion, and degranulation ( 20 , 21 ). |
| MedLine Reference | 12587980:6 |
|---|---|
| Sentence | Our results, therefore, indicate that p38 kinase mediates TNFalpha-induced VCAM-1 expression and cell adhesion, whereas JNK suppresses VCAM-1 expression that is independent to NFkappaB activation. |
| MedLine Reference | 12855409:7 |
|---|
| MedLine Reference | 11818564:1158 |
|---|