| Effect | positive |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:1432:out-urn:agi-cellproc:remodeling::positive |
| Nodes | MAPK14 --+> remodeling |
| References | 4 |
| Connectivity | 2 |
| MedLine Reference | 11359848:1039 |
|---|---|
| Sentence | The data demonstrate that activation of p38 MAPK, mediated by xanthine oxidase-generated oxidant production, is essential for the cytoskeletal remodeling in ECs induced by ICAM- 1 cross-linking or neutrophil adherence. |
| MedLine Reference | 11704547:5 |
|---|---|
| Sentence | Inhibition of tyrosine kinase, phosphoinositol 3-kinase, or p38 MAPK significantly attenuated VEGF-mediated TER, F-actin remodeling, and chemotaxis. |
| MedLine Reference | 12558602:5 |
|---|
| MedLine Reference | 14724572:8 |
|---|