| Effect | positive |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:1432:out-urn:agi-cellproc:shrinkage::positive |
| Nodes | MAPK14 --+> shrinkage |
| References | 2 |
| Connectivity | 2 |
| MedLine Reference | 12226098:1014 |
|---|---|
| Sentence | Cell shrinkage triggered mitogen-activated protein (MAP) kinase cascades leading to the activation of MAP/extracellular signal-regulated kinase 1/2 (ERK1/2) kinase (MEK1/2), and p38 kinase. |
| MedLine Reference | 11093030:5 |
|---|---|
| Sentence | In conclusion, the stimulation of h-sgk transcription by osmotic cell shrinkage is mediated by p38-kinase. |