Regulation :

Effect positive
URN urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-cellproc:damage::positive
Nodes TP53 --+> damage
References 9
Connectivity 2

MedLine Reference 12019168:1146
Sentence Overexpression of bcl-2 can block p53-dependent dissipation of mitochondrial m and apoptosis (40 , 41) .

MedLine Reference 12082016:1023
Sentence Tp53 protein is stabilized in response to a wide variety of cellular stresses including DNA damage, hypoxia, metabolic changes, mitotic spindle disruption, hypoxia, and activated oncogenes ( 3 , 4 ).

MedLine Reference 12496418:1157

MedLine Reference 8895663:5

MedLine Reference 8964480:1

MedLine Reference 9338102:5

MedLine Reference 9448003:8

MedLine Reference 9418855:1013

MedLine Reference 11959917:1107