Regulation :

Effect negative
URN urn:agi-Regulation:inout-urn:agi-llid:1432:out-urn:agi-cellproc:contraction::negative
Nodes MAPK14 ---| contraction
References 6
Connectivity 2

MedLine Reference 11834712:1126
Sentence Our results provide several lines of evidence to indicate that increased p38 MAPK activation markedly inhibits the contractility of cardiac myocytes.

MedLine Reference 10567379:1225
Sentence In addition, this study demonstrates that activation of p38 kinase is essential in the regulatory cell volume increase process, a cell protection mechanism against the physiological hyperosmolarity of the rat kidney medulla.

MedLine Reference 10625698:1214

MedLine Reference 11278444:1226

MedLine Reference 11018034:6

MedLine Reference 15107577:9