Regulation :

Effect positive
URN urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-cellproc:dna%20fragmentation::positive
Nodes TP53 --+> dna fragmentation
References 10
Connectivity 2

MedLine Reference 10446202:1124
Sentence These results correspond to the delayed kinetics in p53-mediated DNA degradation and cell death observed in both lines.

MedLine Reference 12138103:1088

MedLine Reference 8940187:1028

MedLine Reference 9584145:1152

MedLine Reference 10531467:1135

MedLine Reference 10644891:10

MedLine Reference 10567553:1239

MedLine Reference 12615954:1983

MedLine Reference 10051609:1019

Sentence DNA degradation was dependent on both the time of incubation ( Figure 1 , lanes 1-3 and 5-10) and the concentration of added p53 protein (see Figure 2 and Figure 5 ).