| URN | urn:agi-ProtModification:in-urn:agi-llid:2033:inout-urn:agi-llid:7157: |
|---|---|
| Nodes | EP300; TP53; MDM2; MDM4 |
| Modification Type | acetylation |
| References | 1 |
| Connectivity | 4 |
| MedLine Reference | 12162806:1 |
|---|---|
| Sentence | MDM2 inhibits the acetylation of p53 by p300/CBP through a mechanism that requires a stable p53-MDM2 interaction and that is sensitive to the deacetylase inhibitor, TSA. |