| Transport Type | export |
|---|---|
| URN | urn:agi-MolTransport:inout-urn:agi-llid:7157:inout-urn:agi-llid:4193: |
| Nodes | MDM2 ---- TP53 |
| References | 2 |
| Connectivity | 2 |
| Sentence | In response to IR, rapid phosphorylation of p53 by the ATM-CHK2 pathway on serines 15 and 20 leads to release of Mdm2 and stabilization of p53 (Meek, 1999 , and references therein). |
|---|---|
| Journal | Cell |
| Journal Reference | v102 i1 p55 (2000) |
| Journal Link | http://www.cell.com/cgi/content/full/102/1/55 |
| MedLine Reference | 11927554:5 |
|---|---|
| Sentence | Our results indicate that Mdm2 targets both p53 and Tip60, suggesting that these two proteins could be co-regulated with respect to protein stability. |