| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-llid:4193::unknown |
| Nodes | TP53 ---> MDM2 |
| References | 2 |
| Connectivity | 2 |
| MedLine Reference | 14575575:0 |
|---|---|
| Sentence | To study the incidence of PTEN, Mdm2 and p53 expression in different histopathological grades of astrocytoma and the signal transduction mechanism through which PTEN affects Mdm2 and p53 expression. |
| MedLine Reference | 14667141:6 |
|---|---|
| Sentence | An increase in p53 activity was followed by an increase in expression of p53-regulated genes p21 and mdm2. |