| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-cellproc:relaxation::unknown |
| Nodes | MDM2 ---> relaxation |
| References | 1 |
| Connectivity | 2 |
| MedLine Reference | 11823051:7 |
|---|---|
| Sentence | These observations demonstrate that deregulated expression of MDM2 and p53 during megakaryocyte differentiation allow a relaxation of the control over genomic stability, allowing further replicative rounds of DNA synthesis. |