| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-cellproc:oncogenesis::unknown |
| Nodes | MDM2 ---> oncogenesis |
| References | 2 |
| Connectivity | 2 |
| MedLine Reference | 12393902:1025 |
|---|---|
| Sentence | For both of these mechanisms, elevated levels of Mdm2 can inhibit the protective functions of p53 and lead to oncogenesis. |
| MedLine Reference | 12702766:1159 |
|---|---|
| Sentence | These data indicate that HIPK1 is involved in (at least) malignant squamous cell tumor formation in vivo , and suggest that, like Mdm2, HIPK1 can promote oncogenesis. |