Regulation :

Effect positive
URN urn:agi-Regulation:inout-urn:agi-smol:pip3:out-urn:agi-go:0004674::positive
Nodes PIP3 --+> protein serine/threonine kinase
References 1
Connectivity 2

Journal Mol. Cell. Biol
Journal Reference v22 i7 p2304 (2002)
Journal Link http://mcb.asm.org/cgi/content/full/22/7/2304
MedLine Reference 11884615:1047
Sentence PIP3 in turn promotes the activation of the Akt/PKB serine/threonine kinase and a cell survival pathway ( 35 ).