| Effect | negative |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:5728:out-urn:agi-go:0004711::negative |
| Nodes | PTEN ---| RPS6K |
| References | 2 |
| Connectivity | 2 |
| MedLine Reference | 14718524:8 |
|---|---|
| Sentence | Furthermore, expression of PTEN attenuated PDGF-induced signal transduction including phosphatidylinositol 3-kinase and Erk1/2 MAPK activities. |
| MedLine Reference | 9832564:2 |
|---|---|
| Sentence | PTEN expression in glioblastoma cells lacking the protein resulted in inhibition of integrin-mediated MAP kinase activation. |