| Effect | negative |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:5728:out-urn:agi-protfc:cyclin::negative |
| Nodes | PTEN ---| cyclin |
| References | 1 |
| Connectivity | 2 |
| Journal | Mol. Cell. Biol |
|---|---|
| Journal Reference | v23 i17 p6139 (2003) |
| Journal Link | http://mcb.asm.org/cgi/content/full/23/17/6139 |
| MedLine Reference | 12917336:1114 |
| Sentence | Cyclin A, which is the latest cyclin synthesized during the S-phase transition, was decreased in cells expressing PTEN, most likely because of the lack of progression through the cell cycle induced by PTEN. |