Regulation :

Effect unknown
URN urn:agi-Regulation:inout-urn:agi-llid:5728:out-urn:agi-go:0003924::unknown
Nodes PTEN ---> GTPase
References 2
Connectivity 2

Journal J. Cell Biol
Journal Reference v160 i1 p137 (2003)
Journal Link http://www.jcb.org/cgi/content/full/160/1/137
Sentence Additionally, PTEN dephosphorylates the FAK autophosphorylation site during cell detachment, and acts as a lipid phosphatase to negatively regulate rac1 and Cdc42 GTPases and cell migration ( Tamura et al., 1998 , 1999 ; Liliental et al., 2000 ).

Journal J. Cell Biol
Journal Reference v160 i1 p137 (2003)
Journal Link http://www.jcb.org/cgi/content/full/160/1/137
Sentence Additionally, PTEN dephosphorylates the FAK autophosphorylation site during cell detachment, and acts as a lipid phosphatase to negatively regulate rac1 and Cdc42 GTPases and cell migration ( Tamura et al., 1998 , 1999 ; Liliental et al., 2000 ).