| Effect | positive |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:5728:out-urn:agi-go:0004199::positive |
| Nodes | PTEN --+> caspase |
| References | 1 |
| Connectivity | 2 |
| Journal | J. Biol. Chem |
|---|---|
| Journal Reference | v278 i33 p30652 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/33/30652 |
| MedLine Reference | 12788938:1204 |
| Sentence | We have found that PTEN is cleaved upon incubation with HEK293 cellular extracts in the presence of dATP, which activates the caspase cascade in these extracts ( 21 ). |