| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:207:out-urn:agi-enz:3.4.22.17::unknown |
| Nodes | AKT1 ---> calpain |
| References | 1 |
| Connectivity | 2 |
| Journal | J. Biol. Chem |
|---|---|
| Journal Reference | v278 i15 p13422 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/15/13422 |
| MedLine Reference | 12566451:1040 |
| Sentence | Finally, in breast cancer lines, it has been suggested that Akt mediates the calpain degradation of IkappaB protein instead of the consensus ubiquitin pathway ( 28 ). |