Regulation :

Effect positive
URN urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-go:0008083::positive
Nodes MDM2 --+> growth factor activity
References 1
Connectivity 2

Journal J. Biol. Chem
Journal Reference v276 i44 p40583 (2001)
Journal Link http://www.jbc.org/cgi/content/full/276/44/40583
MedLine Reference 11507088:1258
Sentence MDM2 expression can be induced by p53-independent mechanisms such as p53 homologs p63 and p73, activated ras , and growth factors ( 39-41 ).