| Effect | negative |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:5728:out-urn:agi-protfc:tumor%20necrosis%20factor::negative |
| Nodes | PTEN ---| tumor necrosis factor |
| References | 5 |
| Connectivity | 2 |
| MedLine Reference | 11278366:1209 |
|---|---|
| Sentence | Using two different assays, we have shown that MMAC/PTEN can prevent IL-1 and TNF from activating NFkappaB. |
| MedLine Reference | 11356844:1016 |
|---|---|
| Sentence | Expression of PTEN in PC-3 cells to a level comparable with that endogenously present in DU145 cells inhibited TNF activation of NF-kappaB. |
| MedLine Reference | 11799112:1268 |
|---|
| MedLine Reference | 14729949:1349 |
|---|
| MedLine Reference | 11287630:1154 |
|---|