| Effect | positive |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-go:0000130::positive |
| Nodes | MDM2 --+> transcription factor |
| References | 1 |
| Connectivity | 2 |
| Journal | J. Biol. Chem |
|---|---|
| Journal Reference | v275 i34 p26024 (2000) |
| Journal Link | http://www.jbc.org/cgi/content/full/275/34/26024 |
| MedLine Reference | 10856296:1315 |
| Sentence | However, mdm2 is known to bind Rb and derepress the E2F family transcription factors ( 24 ). |