| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:207:out-urn:agi-protfc:oncogene::unknown |
| Nodes | AKT1 ---> oncogene |
| References | 1 |
| Connectivity | 2 |
| Journal | J. Biol. Chem |
|---|---|
| Journal Reference | v274 i34 p24263 (1999) |
| Journal Link | http://www.jbc.org/cgi/content/full/274/34/24263 |
| MedLine Reference | 10446202:1022 |
| Sentence | Cytokines, growth factors, and certain oncogenes have been shown to be effective inhibitors of apoptosis, and in many situations, this anti-apoptotic effect is mediated by the PI3K-induced activation of PKB/Akt ( 18-23 ). |