| Effect | positive |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:207:out-urn:agi-go:0004674::positive:phosphorylation |
| Mechanism | phosphorylation |
| Nodes | AKT1 --+> protein serine/threonine kinase |
| References | 6 |
| Connectivity | 2 |
| MedLine Reference | 11416032:1162 |
|---|---|
| Sentence | Activation of Akt and MAP kinases Erk-1 and -2 As IGF-I can promote cell survival by activating PI3K and its downstream target, the serine-threonine kinase Akt ( 23 ), we determined whether ATA and EB activate Akt in MCF-7 cells. |
| MedLine Reference | 11867632:1197 |
|---|---|
| Sentence | The serine/threonine protein kinase Ark/PKB-induced phosphorylation of eNOS is well established ( 45 , 46 ). |
| MedLine Reference | 9341117:1203 |
|---|
| MedLine Reference | 9679153:1031 |
|---|
| MedLine Reference | 10438924:1066 |
|---|
| MedLine Reference | 10490623:1295 |
|---|