Regulation :

Effect positive
URN urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-go:0005057::positive
Nodes TP53 --+> receptor signaling protein
References 4
Connectivity 2

Journal Cell
Journal Reference v103 i5 p691.1 (2000)
Journal Link http://www.cell.com/cgi/content/full/103/5/691.1
Sentence p53 can directly engage each of the major apoptotic pathways in the cell, stimulating both death receptor signaling and mitochrondrial perturbations, including cytochrome c release ( Figure 2 ).

Journal Cell
Journal Reference v103 i5 p691 (2000)
Journal Link http://www.cell.com/cgi/content/full/103/5/691

Sentence p53 can directly engage each of the major apoptotic pathways in the cell, stimulating both death receptor signaling and mitochrondrial perturbations, including cytochrome c release ( Figure 2 ).

Sentence p53 can directly engage each of the major apoptotic pathways in the cell, stimulating both death receptor signaling and mitochrondrial perturbations, including cytochrome c release ( Figure 2 ).