| Effect | unknown |
|---|---|
| URN | urn:agi-ProtModification:in-urn:agi-llid:207:out-urn:agi-go:0004697::unknown |
| Nodes | AKT1 ---> PKC |
| Modification Type | phosphorylation |
| References | 2 |
| Connectivity | 2 |
| MedLine Reference | 12591726:1024 |
|---|---|
| Sentence | Akt can physically associate with the regulatory domain of PKC (10) , and Akt may phosphorylate PKC under certain conditions (11) . |
| MedLine Reference | 11971024:1243 |
|---|---|
| Sentence | Complicating the picture, the PIP 3 -dependent PDK1, besides playing a critical role in activating PKB, has also been shown to phosphorylate/activate various PKC isoforms ( 27 , 28 , 29 ). |