| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:207:out-urn:agi-cellproc:amplify::unknown |
| Nodes | AKT1 ---> amplify |
| References | 1 |
| Connectivity | 2 |
| Journal | PNAS |
|---|---|
| Journal Reference | v99 i23 p14819 (2002) |
| Journal Link | http://www.pnas.org/cgi/content/full/99/23/14819 |
| MedLine Reference | 12409607:1126 |
| Sentence | Akt regulates cell division by phosphorylating p21 ( 26 ), thereby inhibiting its association with both PCNA and cdk2, while increasing its promotion of cyclinD1-cdk4 assembly ( 27 ). |