| Effect | negative |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-cellproc:morphogenesis::negative |
| Nodes | MDM2 ---| morphogenesis |
| References | 1 |
| Connectivity | 2 |
| MedLine Reference | 9087426:3 |
|---|---|
| Sentence | In six different transgenic mouse lines, deregulated expression of MDM2 inhibited normal development and morphogenesis of the mammary gland, and caused cellular hypertrophy and nuclear abnormalities. |