Regulation :

Effect negative
URN urn:agi-Regulation:inout-urn:agi-llid:5728:out-urn:agi-complex:3105899::negative
Nodes PTEN ---| insulin receptor
References 1
Connectivity 2

MedLine Reference 10556061:4
Sentence Furthermore, we have shown that PTEN acts in the insulin signaling pathway and all signals from the insulin receptor can be antagonized by either Drosophila or human PTEN, suggesting a potential means for alleviating symptoms associated with altered insulin signaling.