| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:207:out-urn:agi-complex:3000215::unknown |
| Nodes | AKT1 ---> IL1 |
| References | 3 |
| Connectivity | 2 |
| MedLine Reference | 12221085:1181 |
|---|---|
| Sentence | Subsequently, similar results were reported for the mechanism of phosphatidylinositol 3-OH-kinase (PI3K ) and PI3K-activated kinase B/Akt-dependent NF-kappaB activation by IL-1 signaling, which was shown to involve the phosphorylation of the RelA/p65 activation domain ( 62 ). |
| MedLine Reference | 10373526:1234 |
|---|---|
| Sentence | Dominant negative Akt blocks IL-1 signaling to an NFkappaB-dependent promoter. |
| MedLine Reference | 14691254:1034 |
|---|