| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-cellproc:G0%27::unknown |
| Nodes | TP53 ---> G0' |
| References | 2 |
| Connectivity | 2 |
| MedLine Reference | 8608941:2 |
|---|---|
| Sentence | However, we found that certain ribonucleotide biosynthesis inhibitors caused a p53-dependent G0 or early G1 arrest in the absence of replicative DNA synthesis or detectable DNA damage in normal human fibroblasts. |
| MedLine Reference | 10419986:1143 |
|---|---|
| Sentence | In fibroblasts, the p53 protein interacts directly with the GAS1 gene product, a plasma membrane glycoprotein that blocks the G 0 to S phase transition (Del Sal et al. 1995 ). |