| Effect | positive |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-cellproc:catabolism::positive |
| Nodes | TP53 --+> catabolism |
| References | 3 |
| Connectivity | 2 |
| Journal | J. Exp. Med |
|---|---|
| Journal Reference | v193 i12 p1361 (2001) |
| Journal Link | http://www.jem.org/cgi/content/full/193/12/1361 |
| Sentence | Like MDM2, which uses CBP to target p53 for degradation ( 47 ), PML and CBP could cooperate to enhance both transcription and catabolism. |
| MedLine Reference | 11080152:1236 |
|---|---|
| Sentence | Interestingly, the type II hexokinase gene, whose overexpression is associated with increased glucose catabolism in cancer cells, is apparently regulated in opposing manners by p53 and GR ( Mathupala et al ., 1997 ). |
| MedLine Reference | 11413191:1245 |
|---|---|
| Sentence | Like MDM2, which uses CBP to target p53 for degradation ( 47 ), PML and CBP could cooperate to enhance both transcription and catabolism. |