Regulation :

Effect unknown
URN urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-cellproc:stability::unknown
Nodes TP53 ---> stability
References 14
Connectivity 2

Journal Cell Sci
Journal Reference v116 i5 p773 (1997)
Journal Link http://jcs.biologists.org/cgi/content/full/116/5/773
MedLine Reference 12571275:1208

MedLine Reference 12036943:1185
Sentence DISCUSSION TOP ABSTRACT INTRODUCTION MATERIALS AND METHODS RESULTS DISCUSSION REFERENCES Wild-type p53 maintains chromosomal stability by controlling the growth arrest and apoptotic responses after a genotoxic stimulus.

MedLine Reference 12727844:1021
Sentence The p53 tumor suppressor gene is a transcription factor that regulates the expression of genes involved in cell-cycle inhibition, apoptosis, genetic stability, and angiogenesis (5) .

MedLine Reference 12874009:1035

MedLine Reference 7499360:1006

MedLine Reference 8647846:1028

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MedLine Reference 11359908:1063

MedLine Reference 10359818:1025

MedLine Reference 15450681:1
Sentence The TP53 tumor suppressor gene, encoding a phosphoprotein, is a key element in maintaining genomic stability and cell apoptosis.

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