Regulation :

Effect unknown
URN urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-cellproc:g1phase::unknown
Nodes MDM2 ---> g1 phase
References 12
Connectivity 2

MedLine Reference 10614665:1264
Sentence Likewise, MDM2 is able to prevent p53-mediated apoptosis in some tumor cell lines ( 34 ) as well as G 1 cell cycle arrest even in the absence of p53 ( 35 ).

MedLine Reference 11877376:1199

MedLine Reference 10075719:1020

MedLine Reference 10567404:1297

MedLine Reference 10906133:1234

MedLine Reference 11278272:1294

MedLine Reference 9292533:0

MedLine Reference 15283159:4

MedLine Reference 12556559:1158

MedLine Reference 12446760:1034

MedLine Reference 12509446:1249

Sentence Mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein.