Regulation :

Effect unknown
URN urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-cellproc:stability::unknown
Nodes MDM2 ---> stability
References 2
Connectivity 2

Journal Cell
Journal Reference v91 i3 p325 (1997)
Journal Link http://www.cell.com/cgi/content/full/91/3/325
MedLine Reference 10207094:1238
Sentence Experiments reported by Midgley and Lane ( 43 ) have shown that expression of Mdm2 after microinjection reduces p53 stability in A431 cells.

Sentence Interestingly, MDM2 was recently reported to regulate p53 stability in cells ( Haupt et al., 1997 ; Kubbutat et al., 1997 ).