| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-cellproc:immunoreactivity::unknown |
| Nodes | MDM2 ---> immunoreactivity |
| References | 1 |
| Connectivity | 2 |
| Journal | Cancer Res |
|---|---|
| Journal Reference | v63 i10 p2616 (2003) |
| Journal Link | http://cancerres.aacrjournals.org/cgi/content/full/63/10/2616 |
| MedLine Reference | 12750288:1097 |
| Sentence | Hdm2 protein is known to be highly phosphorylated at a number of sites that can affect its immunoreactivity with several antibodies (45) , and therefore, we first sought to confirm hdm2 expression levels in the breast cancer cell lines using a second mAb, 2A9 (42) , the epitope for which (amino acids 155...222) is not known to be sensitive to posttranslational modification. |