| Effect | negative |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:7157:out-urn:agi-cellproc:amplify::negative |
| Nodes | TP53 ---| amplify |
| References | 18 |
| Connectivity | 2 |
| Journal | Cell Phys |
|---|---|
| Journal Reference | v279 i3 pC868 (2000) |
| Journal Link | http://ajpcell.physiology.org/cgi/content/full/279/3/C868 |
| MedLine Reference | 10942736:1026 |
| Sentence | The activation of p53 may cause either cell division cycle arrest or apoptosis ( 1 , 9 , 19 , 40 ). |
| MedLine Reference | 10676655:1016 |
|---|---|
| Sentence | INTRODUCTION TOP ABSTRACT INTRODUCTION MATERIALS AND METHODS RESULTS DISCUSSION REFERENCES p53 acts as a checkpoint for cell division in most eukaryotic cells and is normally expressed at low levels with rapid decay kinetics. |
| MedLine Reference | 12670900:1258 |
|---|---|
| Sentence | Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. |
| MedLine Reference | 12750285:1641 |
|---|
| MedLine Reference | 11470757:1257 |
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| MedLine Reference | 12198151:1153 |
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| MedLine Reference | 11124803:1253 |
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| MedLine Reference | 10206959:1022 |
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| MedLine Reference | 10893263:1032 |
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| MedLine Reference | 1501881:4 |
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| MedLine Reference | 8021299:10 |
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| MedLine Reference | 12417790:0 |
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| MedLine Reference | 7819043:10 |
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| MedLine Reference | 7788934:0 |
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| MedLine Reference | 7560890:0 |
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| MedLine Reference | 9572492:0 |
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| MedLine Reference | 12821781:1014 |
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| MedLine Reference | 9294187:1041 |
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