| Effect | unknown |
|---|---|
| URN | urn:agi-Regulation:inout-urn:agi-llid:4193:out-urn:agi-cellproc:proliferation::unknown |
| Nodes | MDM2 ---> proliferation |
| References | 5 |
| Connectivity | 2 |
| MedLine Reference | 9292533:1171 |
|---|---|
| Sentence | Furthermore, MDM2 association with other cell- cycle regulatory proteins, E2F-1, CDK4, and p21, was also studied, since binding of these proteins to MDM2 could also affect proliferation and apoptosis of these MM cells. |
| MedLine Reference | 10766163:1148 |
|---|---|
| Sentence | Discussion TOP ABSTRACT Introduction Materials and Methods Results Discussion REFERENCES The tumor suppressor p53 and the oncogene hdm2 display an essential interplay in regulating cellular proliferation and apoptosis. |
| MedLine Reference | 11861407:1176 |
|---|
| MedLine Reference | 12615721:1380 |
|---|
| MedLine Reference | 11013216:1007 |
|---|